Aponogeton madagascariensis is without comparison among the oddest plants in our aquaria. Instead of normal mesophyll, a lattice full of holes develops and this makes the plant a rarity in every botanical garden or collection of water plants. However, Aponogeton madagascariensis is a very difficult plant to grow and should be kept as a proud solitary plant only in specialised aquaria. It requires a nutrient and calcarious substrate with frequent water replacement because it tends to loose the older leaves in "old water".

Also, Aponogeton madagascariensis prefers diffused indirect light as it comes from shady banks and brooks with no direct sunshine. In all circumstances this is a very diffucul plant to culture also because the many different varieties require quite different environmental conditions. Nowadays, Aponogeton madagascariensis is also produced from tissue cultures.